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2022 Hannover

DG-GT Hybrid Symposium Making Gene Therapy a Clinical Reality

Herrenhausen Palace, Hannover, 23-25 March 2022

Held in collaboration with the Volkswagen Foundation

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DG-GT's Making Gene Therapy a Clinical Reality Symposium took place from 23-25 March 2022 at Herrenhausen Palace, Hannover.


132 delegates attended the event in-person, and 47 attended virtually.


The symposium began with an Education Session for PhD Students, MD Students and MD PhD Students. View Education Session Programme.






Meeting Organisers

Local Organising Committee

- Frank Bengel, Hannover Medical School

- Hildegard Büning, Hannover Medical School

- Tobias Cantz, Hannover Medical School

- Christine Falk, Hannover Medical School

- Boris Fehse, University of Hamburg

- Melanie Galla, Hannover Medical School

- Ulrike Köhl, Fraunhôfer Institute, Leipzig

- Thomas Moritz, Hannover Medical School

- Michael Ott, Hannover Medical School

- Martin Sauer, Hannover Medical School

- Axel Schambach, Hannover Medical School

- Brigitte Schlegelberger, Hannover Medical School

- Thomas Thum, Hannover Medical School


Meeting Partner - Volkswagen Foundation

- Mareike Rüßmann, Volkswagen Foundation



Award Winners

Congratulations to the oral and poster presentation award winners, who presented at the DG-GT Hybrid Symposium in Hannover, 23-25 March 2022.


Oral Presentation Winners

  • Lea Krutzke, University of Ulm Process-related impurities in the ChAdOx1 nCov-19 vaccine

  • Viviane Dettmer-Monaco, Medical Center- University of Freiburg Gene editing of hematopoietic stem cells restores the cytotoxic T cell response in a murine model of familial hemophagocytic lymphohistiocytosis type 3

  • Adrian Schwarzer, Hannover Medical School A four-color AAV6 system for efficient biallelic homology-directed genome editing (HDR) without AAV vector integration into CRISPR-Cas9 induced double-strand breaks

  • Lea-Isabell Schwarze, University Medical Center Hamburg-Eppendorf CCR5-edited CAR T cells for the treatment of HIV-positive cancer patients



Poster Presentation Winners

  • Rajendra Khanal, Hannover Medical School MicroRNAs regulate SARS-CoV-2 infection in primary human hepatocytes by modulating the entry factors ACE2 and TMPRSS2

  • Tobias Bexte, Hospital of the Goethe University Frankfurt; Frankfurt Cancer Institute, Goethe University Frankfurt am Main; University Cancer Center (UCT) Frankfurt CRISPR-Cas9 based gene editing of the immune checkpoint NKG2A enhances NK cell mediated cytotoxicity against multiple myeloma

  • Alice Rovai, Medizinische Hochschule Hannover (MHH) In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice

  • Ala Dibas, University Medical Centre, Freiburg In vitro modeling of CAR T cell induced cytokine release syndrome validates two genetic targets to mitigate the condition


With thanks to our sponsors and partners


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Sekretariat der DG-GT e.V.
Institut für Experimentelle Hämatologie
Hildegard Büning
Carl-Neuberg-Str. 1
30625 Hannover

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© 2021 Die Deutsche Gesellschaft für Gentherapie e.V.

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